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Psoriasis

Psoriasis vulgaris is a chronic skin disease seen in 2% of the world population.

In genetically susceptible individuals, it is triggered by infection, medication, stress, seasonal change, and low vitamin d level.

The disease is often characterized by sharply circumscribed, red-pearl-colored scales on the knees, elbows, and scalp. Lesions may spread to the entire body area. Joint and nail involvement can be seen. There are plaque, guttate, inverse, pustular and erythrodermic types.

There is an increase in the incidence of heart diseases, insulin resistance, diabetes, fatty liver, central obesity, inflammatory bowel diseases, celiac, ulcerative colitis in patients with psoriasis. The diagnosis of psoriasis is often made by dermatological examination. However, a skin biopsy may be performed to confirm the diagnosis.

Topical treatments (moisturizers, topical steroids, topical retinoids, Vitamin D analogues, topical calcineurin inhibitors), systemic treatments (acitretin, methotrexate, cyclosporine, biologics; etanercept, infliximab, adalimumab, ustekinumab, secukinumab, phototherapy treatment) can be used in the treatment of psoriasis.