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Acne

Acne vulgaris is one of the most common skin diseases and is a chronic inflammatory disease of the pilosebaceous unit that affects seborrheic areas such as the face, back and chest.

It is characterized by comedones, papules, pustules, cysts, nodules and cicatricial lesions. The incidence of the disease in adolescence is 90%. However, studies conducted in recent years show that the incidence of the disease increases after adolescence, especially in female patients.

Follicular hyperkeratinization, increased sebum production, increased colonization of Propionibacterium acnes and periglandular dermal inflammation are responsible for the pathogenesis of acne formation.

Cosmetic Acne

It has been used to describe a picture that develops as a result of long-term use of various cosmetic products containing comedogenic substances in women between the ages of 20 and 40. This picture is characterized by mostly closed and sometimes open comedones (white or black buttons) that appear after a few months of use of the cosmetic product. It should be noted that some procedures applied for facial care and skin cleansing may also cause acne.

Late Onset (Adult) Acne

Acne detected after the age of 25 in adults is defined as late-onset (adult) acne. In population-based studies, it has been reported that the prevalence of late-onset acne is around 14%, this rate is 12% in women and 3% in men.

Pregnancy-Acne

While acne lesions may be triggered by hormones (androgen hormones such as testosterone, androstenedione and 17-hydroxyprogesterone) during pregnancy, it regresses in some patients. Acne vulgaris can be triggered by hormone levels, diet, smoking, emotional stress and cosmetics in genetically predisposed individuals. Acne scars, aesthetic It creates social and psychological problems. In addition to the drugs used in acne treatment, it is important to clean the skin, moisturize the skin properly and use sunscreen. In acne vulgaris, it is more appropriate to prescribe dermocosmetic products by physicians.

Acne Treatment

Before starting the treatment, it is important to inform the patients and their families about the pathogenesis, course, complications and treatment duration of acne. Acne treatment can be planned as a topical or systemic treatment according to the clinical severity of the disease. Patient expectation is rapid regression of acne lesions and no recurrence. However, with treatment, the first clinical response is obtained in 6-8 weeks. Depending on the effectiveness of the treatment and the treatment agents used, the treatment is continued for a minimum of three months. The recurrence of the disease cannot be prevented with treatment.

Topical Treatments

  • Topical retinoids: Adapalene, tretinoin, tazarotene, and retinol
  • Benzoyl peroxide
  • Topical antibiotics: Erythromycin, Clindamycin
  • Azelaic Acid
  • AHA: Alpha hydroxy acids: Glycolic acid
  • Beta Hydroxy acid salicylic acid
  • Systemic Treatments
  • Antibiotics (Azithromycin, Tetracycline, Doxycycline)
  • Isotretinoin (Roaccutane, Zoretanin)
  • Birth Control Pills

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