After the summer months, dryness, dullness, fine lines, and an increased tendency toward pigmentation are commonly observed on the skin. Therefore, autumn is one of the most suitable times to restore lost moisture and support the skin’s natural renewal mechanisms.
Mesotherapy procedures performed during this period are often referred to as part of a “seasonal repair protocol.”
What Is Mesotherapy?
Mesotherapy is a treatment in which vitamins, minerals, amino acids, and hyaluronic acid are injected into the middle layer of the skin (the mesoderm) through micro-injections.
The goal is not to immediately alter the surface of the skin but to stimulate cellular regeneration.
This method delivers bioactive substances into deeper layers that topical creams cannot reach, helping achieve a more hydrated, radiant, and balanced complexion.
Why Is Autumn the Ideal Season for Mesotherapy?
In autumn, the intensity of UV rays decreases, and the skin begins to repair the damage left from summer. Factors such as sunlight, saltwater, wind, and heat can lead to moisture loss, reduced elasticity, and pigmentation.
Mesotherapy performed during this season allows for more controlled healing and less sensitivity.
Especially for individuals living in large cities like Istanbul, urban stress, air pollution, and a fast-paced lifestyle can increase the load of free radicals in the skin. Mesotherapy helps rebalance the skin’s metabolic functions during this transitional period.
The Scientific Role of Mesotherapy Ingredients
The success of mesotherapy depends on the quality of the products used and the right combination of active ingredients. Each formulation serves a specific purpose within clinical applications.
1. Jalupro – Amino Acid and Collagen Support
Jalupro contains amino acid complexes that help stimulate collagen synthesis in the skin. These include glycine, proline, lysine, and alanine — the structural building blocks of collagen.
As fibroblast activity decreases with age, elasticity loss and dullness may occur. Jalupro helps slow this process down.
Post-treatment, the goal is to achieve more elastic, firm, and luminous skin — ideal for dry or fine-line-prone complexions.
2. Produktil – Tissue Repair and Pigmentation Support
Produktil contains hyaluronic acid and peptides that activate the skin’s micro-repair mechanisms.
It is particularly useful for pigmentation-prone skin, as it may help regulate melanin synthesis.
When used in autumn, it supports balanced results aimed at reducing uneven skin tone caused by summer exposure.
3. Cellbooster Glow – Radiance and Tone Uniformity
As its name suggests, Cellbooster Glow focuses on boosting skin radiance and color homogeneity. Its formula includes antioxidant agents, hyaluronic acid, and micro-peptides.
Clinical observations show that with consistent treatments, the skin tone becomes more even and “light-reflective.”
This product is preferred for dull, tired, and stressed skin, especially for those living in metropolitan areas like Istanbul, where pollution contributes to a lackluster appearance.
4. Salmon DNA – Plinest / Newest / Chroma Philart / Rejuran
Salmon DNA increases collagen production, helping the skin regain elasticity and vitality.
Its high water-retention capacity deeply hydrates the skin, giving it a plump and luminous look similar to that achieved with hyaluronic acid.
It also helps reduce oxidative stress, protecting against signs of aging.
This therapy is especially preferred for dull, dehydrated, fine-lined, or environmentally damaged skin.
5. Profhilo – Deep Hydration and Tissue Density
Profhilo is a high-purity, hyaluronic-acid-based bio-remodeling agent.
Unlike traditional mesotherapy, it creates a broad reservoir of hydration within the skin.
It supports the extracellular matrix, enhancing the tissue’s ability to retain water.
The result is a plumper, firmer, and more hydrated skin texture.
It is one of the most commonly used formulas for individuals experiencing dryness during the autumn season.
6. Neuvia Hydradelux – “Crystal Youth” Biomimetic Renewal and Intense Moisture
Neuvia Hydradelux is a next-generation biomimetic mesotherapy solution formulated with advanced hyaluronic acid technology.
Its molecular chains mimic the skin’s natural structure, supporting long-lasting hydration while promoting biological renewal.
The formulation contains hyaluronic acid, amino acids (l-proline and glycine), niacinamide, antioxidant complexes, and calcium hydroxyapatite microspheres.
This combination helps strengthen the skin barrier, particularly in dry, sensitive, or fatigued skin.
For individuals exposed to Istanbul’s rapidly changing seasonal conditions, Neuvia Hydradelux helps the skin maintain balanced moisture and radiance, resulting in a more resilient and revitalized appearance.
7. PB Serum Mesotherapy – Enzymatic Skin Renewal Support
PB Serum mesotherapy differs from conventional hyaluronic acid-based treatments thanks to its enzymatic formulations.
It contains collagenase, lipase, and lyase — enzymes that help break down damaged proteins and promote tissue remodeling.
This contributes to smoother, firmer, and more uniform skin texture.
When combined with traditional mesotherapy cocktails, PB Serum can enhance elasticity and refine irregularities.
It is particularly suited for skin showing loss of firmness or uneven texture, applied in sessions prescribed by a dermatologist.
Its enzymatic structure accelerates metabolic renewal, helping the skin activate its natural repair cycle more effectively.
Treatment Planning and Application Discipline
Each patient requires a personalized blend — not every product or dosage fits all.
The dermatologist determines the appropriate formulation based on a detailed skin examination and analysis.
Typically, mesotherapy is performed over 2–4 sessions, spaced about 15–20 days apart.
Mild redness or sensitivity immediately after treatment is normal and usually subsides within hours.
Hydration and radiance improvements are often visible within the first week.
Results and Realistic Expectations
Mesotherapy is not a “miracle treatment” that transforms the skin instantly.
However, with regular sessions, it can significantly improve vitality, tone uniformity, and moisture balance.
Visible benefits often include smoother fine lines, enhanced elasticity, and a more “rested” facial expression.
Factors such as skin type, age, genetics, lifestyle, and adherence to home care routines influence outcomes.
When performed by a qualified dermatologist in sterile conditions, mesotherapy is considered safe.
Nevertheless, results and responses vary between individuals.
A well-planned autumn mesotherapy protocol — combining the right ingredients, medical supervision, and consistent follow-up — can contribute meaningfully to long-term skin health.
Disclaimer: This article is for informational purposes only. Always consult a board-certified dermatologist for diagnosis and treatment recommendations.
